Maze Therapeutics Inc
MAZEHealthcare·Biotechnology·USA·Mid·NASD·Nov 11 • 3:59 PM ET
Price
MAZE against its 20, 50 and 200-day averages31.5% under the 52-week high of 53.65 on 16 Mar 2026. 52-week low 21.95 on 21 Sep 2026. Last 15 sessions, 25.7% high to low
Volume 0.71× normal · the line is the 50-bar volume average
Profile
MAZEMaze Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular, and related metabolic, or CVRM diseases. Its pipeline includes the Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process to refer a variant functionalization. The company was founded by Mark Daly, Aaron D. Gitler, Stephen Elledge, Sekar Kathiresan, and Jonathan S. Weissman on August 29, 2017 and is headquartered in San Francisco, CA.
| Index | RUT |
|---|---|
| Employees | 141 |
| IPO | Jan 31, 2025 |
| Beta | 1.96 |
| ATR, 14d | 1.74 |
| Rel volume | 0.71 |
| Short float | 19.69% |
| Insider own | 37.91% |
| Inst own | 70.73% |
Snapshot
6 groupsValuation
| Index | RUT |
|---|---|
| Market Cap | 2.01B |
| Enterprise Value | 1.68B |
| Income | -151.47M |
| Sales | 20.00M |
| Book/sh | 7.59 |
| Cash/sh | 7.13 |
| Dividend Est. | - |
| Dividend TTM | - |
| Dividend Ex-Date | - |
| Dividend Gr. 3/5Y | - - |
| Payout | - |
| Employees | 141 |
| IPO | Jan 31, 2025 |
Ratios
| P/E | - |
|---|---|
| Forward P/E | - |
| PEG | - |
| P/S | 100.43 |
| P/B | 4.84 |
| P/C | 5.15 |
| P/FCF | - |
| EV/EBITDA | - |
| EV/Sales | 83.92 |
| Quick Ratio | 14.14 |
| Current Ratio | 14.14 |
| Debt/Eq | 0.14 |
| LT Debt/Eq | 0.13 |
| Option/Short | Yes / Yes |
Earnings
| EPS (ttm) | -2.70 |
|---|---|
| EPS next Y | -3.35 |
| EPS next Q | -0.83 |
| EPS this Y | 7.83% |
| EPS next Y | -19.00% |
| EPS next 5Y | -6.41% |
| EPS past 3/5Y | -0.41% - |
| Sales past 3/5Y | - - |
| EPS Y/Y TTM | -19.59% |
| Sales Y/Y TTM | 700.00% |
| EPS Q/Q | -25.93% |
| Sales Q/Q | - |
| Earnings | Nov 09 AMC |
| EPS/Sales Surpr. | -4.03% - |
Ownership
| Insider Own | 37.91% |
|---|---|
| Insider Trans | -2.01% |
| Inst Own | 70.73% |
| Inst Trans | 10.57% |
| ROA | -32.45% |
| ROE | -37.49% |
| ROIC | -31.34% |
| Gross Margin | 91.40% |
| Oper. Margin | -820.82% |
| Profit Margin | -757.36% |
| SMA20 | 14.71% |
| SMA50 | 29.67% |
| SMA200 | 16.77% |
| Trades | - |
Technical
| Shs Outstand | 56.45M |
|---|---|
| Shs Float | 33.95M |
| Short Float | 19.69% |
| Short Ratio | 9.81 |
| Short Interest | 6.68M |
| 52W High | 53.65 -31.54% |
| 52W Low | 21.95 67.33% |
| Volatility | 6.11% 5.52% |
| ATR (14) | 1.74 |
| RSI (14) | 73.85 |
| Beta | 1.96 |
| Rel Volume | 0.71 |
| Avg Volume | 681.69K |
| Volume | 484,188 |
Performance
| Perf Week | 10.04% |
|---|---|
| Perf Month | 37.77% |
| Perf Quarter | 32.77% |
| Perf Half Y | 36.24% |
| Perf YTD | -11.34% |
| Perf Year | 13.86% |
| Perf 3Y | - |
| Perf 5Y | - |
| Perf 10Y | - |
| Recom | 1.00 |
| Target Price | 62.46 |
| Prev Close | 35.45 |
| Price | 36.73 |
| Change % | 3.61% |
Analyst ratings
latest 9 of 9| Date | Action | Analyst | Rating change | Target | Implied |
|---|---|---|---|---|---|
| Oct 19, 2026 | Initiated | CCanaccord Genuity | Buy | $75 | +104.2% |
| Sep 23, 2026 | Initiated | CCitigroup | Buy | $50 | +36.1% |
| Mar 18, 2026 | Initiated | TTruist | Buy | $68 | +85.1% |
| Mar 10, 2026 | Initiated | MMizuho | Outperform | $97 | +164.1% |
| Dec 04, 2025 | Initiated | WWells Fargo | Overweight | $55 | +49.7% |
| Nov 14, 2025 | Initiated | RRaymond James | Outperform | ||
| Sep 02, 2025 | Initiated | BBTIG Research | Buy | $30 | -18.3% |
| Jul 23, 2025 | Initiated | HH.C. Wainwright | Buy | $34 | -7.4% |
| Jul 08, 2025 | Initiated | WWedbush | Outperform | $17 | -53.7% |
Peers
Mkt cap| Ticker | Company | Mkt cap |
|---|---|---|
| TVTX | Travere Therapeutics Inc | 5.00B |
| VERA | Vera Therapeutics Inc | 2.20B |
| VRTX | Vertex Pharmaceuticals Inc | 138.69B |
| PROK | ProKidney Corp | 341.68M |
| JBIO | Jade Biosciences Inc | 1.05B |
| MLYS | Mineralys Therapeutics Inc | 1.43B |
| ARDX | Ardelyx Inc | 786.79M |
| DNLI | Denali Therapeutics Inc | 3.16B |
| CLYM | Climb Bio Inc | 719.55M |
| ADRX | ADARx Pharmaceuticals Inc | 1.47B |
Insider trading
latest 14 of 100| Insider | Relationship | Date | Transaction | Cost | Shares | Value | Total held | Form |
|---|---|---|---|---|---|---|---|---|
| Coloma Jason V | Chief Executive Officer | Nov 02 '26 | Sale | 30.25 | 34,501 | 1,043,766 | 12,965 | Nov 04 04:13 PM |
| Coloma Jason V | Officer | Nov 02 '26 | Proposed Sale | 31.70 | 34,501 | 1,093,682 | Nov 02 04:04 PM | |
| Dandekar Atul | CSBO | Oct 29 '26 | Option Exercise | 10.42 | 7,500 | 78,150 | 39,816 | Oct 30 04:14 PM |
| Dandekar Atul | CSBO | Oct 29 '26 | Sale | 32.07 | 7,500 | 240,532 | 32,316 | Oct 30 04:14 PM |
| ATUL DANDEKAR | Officer | Oct 29 '26 | Proposed Sale | 31.73 | 15,000 | 475,950 | Oct 29 04:21 PM | |
| Coloma Jason V | Chief Executive Officer | Oct 01 '26 | Sale | 27.02 | 34,501 | 932,260 | 15,558 | Oct 02 04:12 PM |
| Bernstein Harold | President, R&D & CMO | Oct 01 '26 | Option Exercise | 10.42 | 16,141 | 168,189 | 16,141 | Oct 02 04:09 PM |
| Bernstein Harold | President, R&D & CMO | Oct 01 '26 | Sale | 26.93 | 16,141 | 434,743 | 0 | Oct 02 04:09 PM |
| HAROLD BERNSTEIN | Officer | Oct 01 '26 | Proposed Sale | 27.18 | 16,141 | 438,712 | Oct 01 04:21 PM | |
| Dandekar Atul | CSBO | Sep 29 '26 | Option Exercise | 10.42 | 7,500 | 78,150 | 39,816 | Oct 01 04:06 PM |
| Dandekar Atul | CSBO | Sep 29 '26 | Sale | 27.06 | 7,500 | 202,921 | 32,316 | Oct 01 04:06 PM |
| Coloma Jason V | Officer | Oct 01 '26 | Proposed Sale | 27.05 | 34,501 | 933,252 | Oct 01 04:02 PM | |
| Bernstein Harold | President, R&D & CMO | Sep 04 '26 | Sale | 26.22 | 9,705 | 254,502 | 0 | Sep 08 04:20 PM |
| HAROLD BERNSTEIN | Officer | Sep 04 '26 | Proposed Sale | 25.87 | 9,705 | 251,068 | Sep 04 04:34 PM |
Held by
AUM| Ticker | Company | AUM |
|---|---|---|
| VTI | Vanguard Morningstar Total Stock Market ETF | AUM: 687.42B |
| IWM | iShares Russell 2000 Index Fund | AUM: 77.38B |
| XPH | State Street SPDR S&P Pharmaceuticals ETF | AUM: 516.35M |
| VXF | Vanguard Extended Market Index ETF | AUM: 30.47B |
| IWO | iShares Russell 2000 Growth ETF | AUM: 14.06B |
| IBB | iShares Biotechnology ETF | AUM: 11.36B |
| SCHA | Schwab U.S. Small-Cap ETF | AUM: 22.25B |
| VTWO | Vanguard Russell 2000 Index ETF | AUM: 16.75B |
| IHE | iShares U.S. Pharmaceuticals ETF | AUM: 1.72B |
| FYC | First Trust Small Cap Growth AlphaDEX Fund | AUM: 1.35B |
News
latest 14 of 104- Maze Therapeutics Reports Third Quarter 2026 Financial Results and Recent Highlights (GlobeNewswire)
- Maze Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire) +6.19%
- Maze Therapeutics to Present Data from MZE829 and MZE782 Programs at ASN Kidney Week 2026 (GlobeNewswire)
- Maze Therapeutics Shares Rise 2.9% After CIBC Initiates Coverage (InvestorsHub)
- Twin Moves: VRTX Rises On Kidney Disease Trial Results, MAZE Rallies Harder (Stocktwits) +26.75%
- Vertex's Kidney Drug Success Sparks a 22% Surge for This Rival Biotech (Barrons.com)
- Maze Therapeutics to Participate in Three Upcoming Investor Conferences (GlobeNewswire)
- Maze Therapeutics Announces Appointments to Its Board of Directors (GlobeNewswire)
- Maze Therapeutics Reports Second Quarter 2026 Financial Results and Recent Highlights (GlobeNewswire)
- Maze Therapeutics to Participate in Two Upcoming Investor Conferences (GlobeNewswire)
- Maze Therapeutics Reports First Quarter 2026 Financial Results and Recent Highlights (GlobeNewswire)
- Maze Therapeutics Announces $150 Million Registered Offering (GlobeNewswire)
- Disney upgraded, Nike downgraded: Wall Street's top analyst calls (The Fly)
- After Plunging 30.8% in 4 Weeks, Here's Why the Trend Might Reverse for Maze Therapeutics, Inc. (MAZE) (Quartz)
Quarterly earnings
actual against estimate| Period | Reported | EPS act | EPS est | EPS rep | Sales act | Sales est | Analysts |
|---|---|---|---|---|---|---|---|
| 2026Q3 | 2026-11-09 | -0.790 | -0.759 | -0.790 | 0.00 | 0.00 | 13 |
| 2026Q2 | 2026-08-11 | -0.760 | -0.717 | -0.758 | 0.00 | 2.86 | 11 |
| 2026Q1 | 2026-05-12 | -0.450 | -0.577 | -0.449 | 20.00 | 10.63 | 11 |
| 2025Q4 | 2026-03-25 | -0.650 | -0.714 | -0.701 | 0.00 | 0.00 | 12 |
| 2025Q3 | 2025-11-06 | -0.660 | -0.708 | -0.626 | 0.00 | 0.00 | 7 |
| 2025Q2 | 2025-08-12 | -0.770 | -0.836 | -0.768 | 0.00 | 3.13 | 6 |
| 2025Q1 | 2025-05-14 | -1.150 | -0.723 | -0.749 | 0.00 | 0.00 | 4 |
| 2024Q4 | 2025-03-31 | -18.320 | 2.050 | -0.112 | 0.00 | 0.00 | 2 |
| 2026Q4 | - | - | -0.831 | - | - | 0.00 | 13 |
| 2027Q1 | - | - | -0.804 | - | - | 2.54 | 9 |
| 2027Q2 | - | - | -0.820 | - | - | 2.54 | 9 |
| 2027Q3 | - | - | -0.854 | - | - | 2.54 | 9 |
| 2027Q4 | - | - | -0.838 | - | - | 4.58 | 9 |
Annual earnings
| Period | EPS act | EPS est | EPS rep | Sales act | Sales est |
|---|---|---|---|---|---|
| 2024FY | 1.250 | -7.883 | 0.078 | 167.5 | 167.67 |
| 2025FY | -3.050 | -3.119 | -3.110 | 0.00 | 0.00 |
| 2026FY | - | -2.811 | - | - | 20.00 |
| 2027FY | - | -3.345 | - | - | 9.73 |
| 2028FY | - | -3.675 | - | - | 10.11 |
| 2029FY | - | -3.769 | - | - | 43.70 |
| 2030FY | - | -2.778 | - | - | 196.07 |
Estimate revisions
last 14 periods| Period | Type | Date | Estimates | Up | Down | Mean | Low | High |
|---|---|---|---|---|---|---|---|---|
| 2026Q4 | S | 2026-11-10 | 9 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-11-09 | 9 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-10-16 | 9 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-09-23 | 8 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-08-12 | 7 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-07-27 | 7 | 0 | 0 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-07-05 | 7 | 0 | 1 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-06-13 | 8 | 0 | 1 | 0.00 | 0.00 | 0.00 |
| 2026Q4 | S | 2026-05-13 | 9 | 0 | 1 | 0.33 | 0.00 | 3.00 |
| 2026Q4 | S | 2026-04-06 | 8 | 1 | 0 | 1.00 | 0.00 | 5.00 |
| 2026Q4 | S | 2026-03-27 | 8 | 1 | 0 | 0.38 | 0.00 | 3.00 |
| 2026Q4 | S | 2026-03-25 | 7 | 1 | 0 | 0.43 | 0.00 | 3.00 |
| 2026Q4 | S | 2026-03-16 | 7 | 0 | 0 | 0.43 | 0.00 | 3.00 |
| 2026Q4 | S | 2026-02-23 | 6 | 0 | 0 | 0.50 | 0.00 | 3.00 |
Estimate history
| EPS, annual | -2.626 | -2.294 | 0.078 | -2.658 | -2.6961 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Period | 2022 | 2023 | 2024 | 2025 | TTM | ||||
| EPS, quarterly | -0.055 | -0.112 | -0.749 | -0.768 | -0.626 | -0.701 | -0.449 | -0.758 | -0.788 |
| Period | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 | Q2 '26 | Q3 '26 |
| Sales, annual | 0 | 0 | 167.5 | 0 | 20 | ||||
| Period | 2022 | 2023 | 2024 | 2025 | TTM | ||||
| Sales, quarterly | 2.5 | 0 | 0 | 0 | 0 | 0 | 20 | 0 | 0 |
| Period | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 | Q2 '26 | Q3 '26 |
| Shares, annual | 43.777 | 43.777 | 43.796 | 49.336 | 56.449 | ||||
| Period | 2022 | 2023 | 2024 | 2025 | MRQ | ||||
| Shares, quarterly | 43.777 | 43.796 | 43.797 | 43.851 | 48.077 | 49.336 | 49.738 | 55.505 | 56.449 |
| Period | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 | Q2 '26 | Q3 '26 |
Income statement, annual
| Metric | TTM | 2025FY | 2024FY | 2023FY | 2022FY |
|---|---|---|---|---|---|
| Total Revenue | 20.00 | 0.00 | 167.50 | 0.00 | 0.00 |
| Cost of Goods Sold Incl. D&A | 1.72 | 2.40 | 3.30 | 4.09 | 3.82 |
| Gross Profit | 18.28 | -2.40 | 164.20 | -4.09 | -3.82 |
| Selling, General and Administrative Excl. Other | 182.44 | 140.50 | 106.62 | 94.46 | 107.21 |
| Research and Development | 135.66 | 108.45 | 83.50 | 73.94 | 88.19 |
| Other Operating Expense | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Operating Income | -164.16 | -142.90 | 57.59 | -98.55 | -111.03 |
| Interest Expense | 2.77 | 0.00 | - | - | - |
| Unusual Expense | 0.00 | 0.00 | 8.44 | 3.83 | 2.40 |
| Net Income Before Taxes | -151.47 | -131.12 | 53.40 | -100.42 | -114.94 |
| Income Taxes | 0.00 | 0.00 | 1.17 | 0.00 | 0.00 |
| Consolidated Net Income | -151.47 | -131.12 | 18.38 | -100.42 | -114.94 |
| Net Income From Continuing Operations | -151.47 | -131.12 | 18.38 | -100.42 | -114.94 |
| Net Income | -151.47 | -131.12 | 3.40 | -100.42 | -114.94 |
| EPS (Recurring) | -2.49 | -2.66 | 0.21 | -2.23 | -2.59 |
| EPS (Basic, Before Extraordinaries) | -2.70 | -2.66 | 0.08 | -2.29 | -2.63 |
| EPS (Diluted) | -2.70 | -2.66 | 0.08 | -2.29 | -2.63 |
| EBITDA | -162.44 | -140.50 | 60.88 | -94.46 | -107.21 |
| Non-Operating Income (Expense) | 15.46 | 11.78 | 4.25 | 1.97 | -1.51 |
| Other After Tax Adjustments | 0.00 | 0.00 | -33.85 | 0.00 | 0.00 |
| Stock Option Compensation Expense | 30.91 | 16.40 | 7.62 | 8.75 | 6.74 |
| Price To Sales Ratio | 82.72 | - | - | - | - |
| Gross Margin | 91.40 | - | 98.03 | - | - |
| Operating Margin | -820.82 | - | 34.38 | - | - |
| Net Margin | -757.36 | - | 2.03 | - | - |
| Shares Outstanding | 56.45 | 49.34 | 43.80 | 43.78 | 43.78 |
| Market Capitalization | 2,040.32 | 2,040.32 | 1,927.18 | - | - |
Income statement, quarterly
| Metric | 2026Q3 | 2026Q2 | 2026Q1 | 2025Q4 | 2025Q3 | 2025Q2 | 2025Q1 | 2024Q4 |
|---|---|---|---|---|---|---|---|---|
| Total Revenue | 0.00 | 0.00 | 20.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Cost of Goods Sold Incl. D&A | 0.39 | 0.39 | 0.44 | 0.50 | 0.57 | 0.65 | 0.68 | 0.70 |
| Gross Profit | -0.39 | -0.39 | 19.56 | -0.50 | -0.57 | -0.65 | -0.68 | -0.70 |
| Selling, General and Administrative Excl. Other | 51.13 | 47.64 | 46.11 | 37.56 | 32.39 | 35.83 | 34.72 | 29.02 |
| Research and Development | 39.84 | 34.55 | 33.70 | 27.57 | 25.19 | 28.11 | 27.58 | 22.22 |
| Other Operating Expense | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Operating Income | -51.52 | -48.03 | -26.55 | -38.06 | -32.97 | -36.47 | -35.40 | -29.73 |
| Interest Expense | 0.97 | 0.93 | 0.87 | 0.00 | - | - | - | - |
| Unusual Expense | 0.00 | 0.00 | 0.00 | 0.00 | -0.20 | -0.10 | 0.00 | 1.54 |
| Net Income Before Taxes | -47.97 | -44.73 | -24.21 | -34.57 | -30.09 | -33.68 | -32.79 | -29.85 |
| Income Taxes | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | -0.28 |
| Consolidated Net Income | -47.97 | -44.73 | -24.21 | -34.57 | -30.09 | -33.68 | -32.79 | 10.07 |
| Net Income From Continuing Operations | -47.97 | -44.73 | -24.21 | -34.57 | -30.09 | -33.68 | -32.79 | 10.07 |
| Net Income | -47.97 | -44.73 | -24.21 | -34.57 | -30.09 | -33.68 | -32.79 | -4.91 |
| EPS (Recurring) | -0.79 | -0.76 | -0.45 | -0.70 | -0.63 | -0.77 | -0.75 | -0.09 |
| EPS (Basic, Before Extraordinaries) | -0.79 | -0.76 | -0.45 | -0.70 | -0.63 | -0.77 | -0.75 | -0.11 |
| EPS (Diluted) | -0.79 | -0.76 | -0.45 | -0.70 | -0.63 | -0.77 | -0.75 | -0.11 |
| EBITDA | -51.13 | -47.64 | -26.11 | -37.56 | -32.39 | -35.83 | -34.72 | -29.02 |
| Non-Operating Income (Expense) | 4.52 | 4.24 | 3.21 | 3.49 | 2.68 | 2.69 | 2.62 | 1.42 |
| Other After Tax Adjustments | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 39.65 |
| Stock Option Compensation Expense | 8.54 | 9.19 | 7.11 | 6.07 | 3.86 | 3.24 | 3.23 | 2.25 |
| Price To Sales Ratio | 82.72 | 88.02 | 80.44 | - | - | 215.22 | - | - |
| Gross Margin | - | - | 97.78 | - | - | - | - | - |
| Operating Margin | - | - | -132.76 | - | - | - | - | - |
| Net Margin | - | - | -121.04 | - | - | - | - | - |
| Shares Outstanding | 56.45 | 55.50 | 49.74 | 49.34 | 48.08 | 43.85 | 43.80 | 43.80 |
| Market Capitalization | 2,040.32 | 1,651.50 | 1,483.80 | 1,993.59 | 1,137.05 | 537.39 | 481.98 | 499.93 |
Balance sheet, annual
| Metric | 2025FY | 2024FY | 2023FY | 2022FY |
|---|---|---|---|---|
| Cash & Short Term Investments | 341.92 | 196.81 | 29.16 | 99.92 |
| Short Term Receivables | 1.50 | 0.00 | 0.00 | 0.00 |
| Inventories | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Current Assets | 6.30 | 4.86 | 4.95 | 6.23 |
| Total Current Assets | 349.72 | 201.67 | 34.11 | 106.15 |
| Net Property, Plant & Equipment | 25.16 | 29.92 | 34.98 | 41.23 |
| Total Investments and Advances | 19.20 | 1.09 | 1.09 | 1.21 |
| Other Assets | 3.05 | 7.87 | 1.32 | 1.37 |
| Total Assets | 397.13 | 240.54 | 71.50 | 149.96 |
| Short Term Debt Incl. Current Port. of LT Debt | 4.79 | 4.63 | 4.49 | 4.32 |
| Accounts Payable | 1.79 | 1.94 | 2.02 | 1.58 |
| Other Current Liabilities | 15.97 | 14.10 | 9.81 | 14.87 |
| Total Current Liabilities | 22.56 | 20.67 | 16.32 | 20.78 |
| Long Term Debt | 18.51 | 22.00 | 45.13 | 27.73 |
| Provision for Risks Charges | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Liabilities | 1.09 | 0.97 | 0.00 | 0.00 |
| Total Liabilities | 42.16 | 43.64 | 61.45 | 48.51 |
| Non-Equity Reserves | 0.00 | 0.00 | 0.00 | 0.00 |
| Preferred Stock - Carrying Value | 0.00 | 508.09 | 383.90 | 383.90 |
| Common Equity | 354.97 | -311.18 | -373.85 | -282.46 |
| Total Shareholders Equity | 354.97 | 196.90 | 10.05 | 101.44 |
| Accumulated Minority Interest | 0.00 | 0.00 | 0.00 | 0.00 |
| Total Equity | 354.97 | 196.90 | 10.05 | 101.44 |
| Total Liabilities & Stockholders Equity | 397.13 | 240.54 | 71.50 | 149.96 |
| Book Value Per Share | 7.19 | -7.11 | -8.54 | -6.45 |
| Tangible Book Value Per Share | 7.19 | -7.11 | -8.54 | -6.45 |
| Full-Time Employees | 141 | 125 | - | - |
| Price to Book Ratio | 4.84 | 5.07 | - | - |
| Return on Assets | -41.12 | 11.78 | -90.68 | - |
| Return on Equity | -47.52 | 17.76 | -180.12 | - |
| Return on Invested Capital | -35.11 | 8.40 | -181.95 | -88.98 |
| Quick Ratio | 15.50 | 9.76 | 2.09 | 5.11 |
| Current Ratio | 15.50 | 9.76 | 2.09 | 5.11 |
Cash flow, annual
| Metric | TTM | 2025FY | 2024FY | 2023FY | 2022FY |
|---|---|---|---|---|---|
| Net Income | -151.47 | -131.12 | 52.23 | -100.42 | -114.94 |
| Depreciation | 1.72 | 2.40 | 3.30 | 4.09 | 3.82 |
| Other Funds (Non Cash) | 34.56 | 19.05 | 21.95 | 15.81 | 15.15 |
| Funds from Operations | -115.20 | -109.67 | 77.48 | -80.51 | -95.97 |
| Extraordinary Item | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Changes in Working Capital | 0.46 | -2.27 | -1.52 | -6.32 | -3.24 |
| Cash from Operating Activities | -114.74 | -111.94 | 75.95 | -86.83 | -99.20 |
| Capital Expenditures | -0.52 | -0.79 | -1.15 | -0.44 | -1.97 |
| Net Assets From Acquisitions | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Sale of Fixed Assets and Businesses | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Purchase or Sale of Investments | -256.51 | -170.17 | 0.00 | 0.00 | -1.20 |
| Purchase of Investments | -375.01 | -187.67 | 0.00 | 0.00 | -1.20 |
| Sale Or Maturity of Investments | 118.50 | 17.50 | 0.00 | 0.00 | 0.00 |
| Other Uses | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Sources | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Cash from Investing Activities | -257.03 | -170.96 | -1.15 | -0.44 | -3.17 |
| Cash Dividends Paid | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Change in Capital Stock | 170.69 | 275.84 | 68.37 | 0.21 | 1.73 |
| Repurchase of Common Pref Stock | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Sale of Common Pref Stock | 170.69 | 275.84 | 68.37 | 0.21 | 1.73 |
| Proceedsfrom Stock Options | 160.32 | 270.27 | 67.64 | 0.00 | 1.57 |
| Issuance or Reduction of Debt, Net | 38.46 | 0.00 | 24.48 | 16.18 | 0.00 |
| Change in Long Term Debt | 38.46 | 0.00 | 24.48 | 16.18 | 0.00 |
| Issuance of Long Term Debt | 38.46 | 0.00 | 24.48 | 16.18 | 0.00 |
| Reduction of Long Term Debt | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Net Financing Active Other Cash Flow | 0.00 | -0.50 | 0.00 | 0.00 | 0.00 |
| Other Financing Activities Uses | 0.00 | -0.50 | 0.00 | 0.00 | 0.00 |
| Cash from Financing Activities | 209.15 | 275.34 | 92.85 | 16.39 | 1.73 |
| Net Change in Cash | -162.62 | -7.57 | 167.65 | -70.88 | -100.64 |
| Free Cash Flow | -115.26 | -112.73 | 74.81 | -87.27 | -101.17 |
| Preferred Dividends (Cash Flow) | - | 0.00 | - | 0.00 | 0.00 |
| Deferred Taxes & Investment Tax Credit | - | 0.00 | 0.00 | 0.00 | 0.00 |
Balance sheet, quarterly
| Metric | 2026Q3 | 2026Q2 | 2026Q1 | 2025Q4 | 2025Q3 | 2025Q2 |
|---|---|---|---|---|---|---|
| Cash & Short Term Investments | 389.66 | 411.09 | 352.38 | 341.92 | 383.94 | 264.54 |
| Short Term Receivables | 3.20 | 2.80 | 21.80 | 1.50 | 0.70 | 0.00 |
| Inventories | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Current Assets | 7.24 | 6.54 | 5.60 | 6.30 | 6.67 | 6.61 |
| Total Current Assets | 400.10 | 420.42 | 379.78 | 349.72 | 391.30 | 271.15 |
| Net Property, Plant & Equipment | 21.94 | 22.83 | 23.97 | 25.16 | 26.46 | 27.71 |
| Total Investments and Advances | 88.41 | 84.91 | 11.64 | 19.20 | 1.09 | 1.09 |
| Other Assets | 1.10 | 3.46 | 4.32 | 3.05 | 3.21 | 3.57 |
| Total Assets | 511.56 | 531.62 | 419.71 | 397.13 | 422.06 | 303.52 |
| Short Term Debt Incl. Current Port. of LT Debt | 4.93 | 4.88 | 4.84 | 4.79 | 4.76 | 4.72 |
| Accounts Payable | 4.57 | 2.21 | 4.01 | 1.79 | 2.92 | 3.67 |
| Other Current Liabilities | 18.80 | 15.87 | 12.38 | 15.97 | 14.43 | 11.52 |
| Total Current Liabilities | 28.30 | 22.96 | 21.24 | 22.56 | 22.11 | 19.90 |
| Long Term Debt | 54.71 | 55.54 | 56.38 | 18.51 | 19.42 | 20.29 |
| Provision for Risks Charges | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Liabilities | 0.00 | 0.00 | 0.39 | 1.09 | 1.09 | 1.09 |
| Total Liabilities | 83.01 | 78.50 | 78.01 | 42.16 | 42.62 | 41.28 |
| Non-Equity Reserves | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Preferred Stock - Carrying Value | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Common Equity | 428.55 | 453.12 | 341.70 | 354.97 | 379.44 | 262.24 |
| Total Shareholders Equity | 428.55 | 453.12 | 341.70 | 354.97 | 379.44 | 262.24 |
| Accumulated Minority Interest | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Total Equity | 428.55 | 453.12 | 341.70 | 354.97 | 379.44 | 262.24 |
| Total Liabilities & Stockholders Equity | 511.56 | 531.62 | 419.71 | 397.13 | 422.06 | 303.52 |
| Book Value Per Share | 7.59 | 8.16 | 6.87 | 7.19 | 7.89 | 5.98 |
| Tangible Book Value Per Share | 7.59 | 8.16 | 6.87 | 7.19 | 7.89 | 5.98 |
| Full-Time Employees | - | - | - | 141 | - | - |
| Price to Book Ratio | 4.84 | 4.34 | 4.15 | 5.25 | 4.34 | 1.84 |
| Return on Assets | -32.45 | -31.99 | -32.57 | -41.12 | -28.15 | - |
| Return on Equity | -37.49 | -37.35 | -38.67 | -47.52 | -36.13 | - |
| Return on Invested Capital | -9.93 | -8.79 | -6.08 | -9.26 | -7.54 | -11.92 |
| Quick Ratio | 14.14 | 18.31 | 17.88 | 15.50 | 17.70 | 13.63 |
| Current Ratio | 14.14 | 18.31 | 17.88 | 15.50 | 17.70 | 13.63 |
Cash flow, quarterly
| Metric | 2026Q3 | 2026Q2 | 2026Q1 | 2025Q4 | 2025Q3 | 2025Q2 |
|---|---|---|---|---|---|---|
| Net Income | -47.97 | -44.73 | -24.21 | -34.57 | -30.09 | -33.68 |
| Depreciation | 0.39 | 0.39 | 0.44 | 0.50 | 0.57 | 0.65 |
| Other Funds (Non Cash) | 9.42 | 10.16 | 8.33 | 6.65 | 4.37 | 4.02 |
| Funds from Operations | -38.17 | -34.17 | -15.44 | -27.42 | -25.14 | -29.01 |
| Extraordinary Item | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Changes in Working Capital | 5.33 | 19.12 | -23.68 | -0.31 | 0.50 | -1.04 |
| Cash from Operating Activities | -32.84 | -15.05 | -39.11 | -27.73 | -24.64 | -30.05 |
| Capital Expenditures | -0.29 | -0.11 | -0.09 | -0.03 | -0.07 | -0.39 |
| Net Assets From Acquisitions | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Sale of Fixed Assets and Businesses | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Purchase or Sale of Investments | -31.12 | -128.40 | 6.37 | -103.35 | -66.81 | 0.00 |
| Purchase of Investments | -68.12 | -162.40 | -23.63 | -120.85 | -66.81 | 0.00 |
| Sale Or Maturity of Investments | 37.00 | 34.00 | 30.00 | 17.50 | 0.00 | 0.00 |
| Other Uses | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Sources | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Cash from Investing Activities | -31.41 | -128.51 | 6.28 | -103.39 | -66.88 | -0.39 |
| Cash Dividends Paid | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Preferred Dividends (Cash Flow) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Change in Capital Stock | 15.77 | 147.49 | 3.84 | 3.59 | 143.76 | 0.61 |
| Repurchase of Common Pref Stock | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Sale of Common Pref Stock | 15.77 | 147.49 | 3.84 | 3.59 | 143.76 | 0.61 |
| Proceedsfrom Stock Options | 14.60 | 145.79 | -0.24 | 0.16 | 141.75 | 0.61 |
| Issuance or Reduction of Debt, Net | 0.00 | -0.05 | 38.52 | 0.00 | 0.00 | 0.00 |
| Change in Long Term Debt | 0.00 | -0.05 | 38.52 | 0.00 | 0.00 | 0.00 |
| Issuance of Long Term Debt | 0.00 | -0.05 | 38.52 | 0.00 | 0.00 | 0.00 |
| Reduction of Long Term Debt | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Net Financing Active Other Cash Flow | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Other Financing Activities Uses | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Cash from Financing Activities | 15.77 | 147.44 | 42.36 | 3.59 | 143.76 | 0.61 |
| Net Change in Cash | -48.49 | 3.88 | 9.52 | -127.53 | 52.23 | -29.83 |
| Free Cash Flow | -33.13 | -15.16 | -39.21 | -27.76 | -24.71 | -30.45 |
Revenue breakdown
| Biological Products, (No Diagnostic Substances) | 2024: 167.50M |
|---|---|
| United States | 2024: 167.50M |
Short interest
shares short against float, oldest to newest| Settlement | Of float | Shares short | Float | Avg volume |
|---|---|---|---|---|
| 2026-10-30 | 19.38% | 6.7M | 34.5M | 657.73K |
| 2026-10-15 | 21.83% | 7.5M | 34.5M | 587.87K |
| 2026-09-30 | 19.04% | 6.6M | 34.5M | 570.63K |
| 2026-09-15 | 16.48% | 5.7M | 34.5M | 551.48K |
| 2026-08-31 | 17.24% | 5.9M | 34.3M | 548.01K |
| 2026-08-14 | 17.41% | 6.0M | 34.4M | 561.59K |
| 2026-07-31 | 16.44% | 5.7M | 34.5M | 590.10K |
| 2026-07-15 | 16.01% | 5.5M | 34.5M | 668.10K |
| 2026-06-30 | 16.02% | 5.5M | 34.5M | 742.70K |
| 2026-06-15 | 11.78% | 4.1M | 34.5M | 851.74K |
| 2026-05-29 | 11.33% | 3.9M | 34.4M | 862.86K |
| 2026-05-15 | 11.50% | 4.0M | 34.4M | 852.50K |
| 2026-04-30 | 13.90% | 4.3M | 31.3M | 869.39K |
| 2026-04-15 | 13.48% | 3.8M | 28.2M | 820.14K |
| 2026-03-31 | 14.18% | 3.9M | 27.4M | 704.70K |
| 2026-03-13 | 13.52% | 3.6M | 26.6M | 481.40K |
| 2026-02-27 | 12.95% | 3.4M | 26.6M | 450.44K |
| 2026-02-13 | 12.64% | 3.4M | 26.6M | 464.77K |
| 2026-01-30 | 10.50% | 2.7M | 26.1M | 427.71K |
| 2026-01-15 | 9.88% | 2.6M | 26.1M | 395.98K |
Option chain
expiry 2026-11-20| Type | Strike | Bid | Ask | Last | IV | Open int | Volume | Delta | Theta | Vega |
|---|---|---|---|---|---|---|---|---|---|---|
| call | 12.50 | 22.50 | 26.50 | 0.00 | 7.633 | 0.00 | 0.00 | 0.966 | -0.119 | 0.004 |
| call | 15.00 | 20.00 | 24.00 | 0.00 | 6.495 | 0.00 | 0.00 | 0.959 | -0.117 | 0.005 |
| call | 17.50 | 17.50 | 21.50 | 0.00 | 5.568 | 0.00 | 0.00 | 0.951 | -0.115 | 0.006 |
| call | 20.00 | 15.00 | 19.00 | 0.00 | 4.782 | 0.00 | 0.00 | 0.942 | -0.111 | 0.007 |
| call | 22.50 | 12.50 | 16.50 | 7.80 | 4.095 | 23.00 | 0.00 | 0.931 | -0.107 | 0.008 |
| call | 25.00 | 10.00 | 14.50 | 4.41 | 3.828 | 300 | 0.00 | 0.917 | -0.102 | 0.009 |
| call | 30.00 | 5.70 | 9.30 | 7.00 | 2.558 | 764 | 32.00 | 0.872 | -0.088 | 0.012 |
| call | 35.00 | 1.90 | 5.00 | 2.85 | 0.898 | 79.00 | 2.00 | 0.623 | -0.233 | 0.022 |
| call | 40.00 | 0.00 | 4.70 | 1.25 | 1.869 | 7.00 | 0.00 | 0.437 | -0.232 | 0.023 |
| call | 45.00 | 0.00 | 4.90 | 0.45 | 2.576 | 5.00 | 0.00 | 0.367 | -0.305 | 0.021 |
| call | 50.00 | 0.00 | 4.90 | 0.50 | 3.055 | 5.00 | 0.00 | 0.332 | -0.348 | 0.021 |
| call | 55.00 | 0.00 | 4.90 | 0.10 | 3.150 | 65.00 | 0.00 | 0.282 | -0.345 | 0.019 |
| call | 60.00 | 0.00 | 4.90 | 0.25 | 2.156 | 72.00 | 0.00 | 0.098 | -0.121 | 0.010 |
| call | 65.00 | 0.00 | 4.90 | 0.50 | 2.432 | 38.00 | 0.00 | 0.090 | -0.124 | 0.009 |
| call | 70.00 | 0.00 | 4.90 | 0.50 | 2.649 | 4.00 | 0.00 | 0.085 | -0.129 | 0.009 |
| call | 75.00 | 0.00 | 4.90 | 0.20 | 2.846 | 6.00 | 0.00 | 0.080 | -0.133 | 0.008 |
| put | 12.50 | 0.00 | 4.90 | 0.20 | 10.861 | 2.00 | 0.00 | -0.070 | -0.455 | 0.008 |
| put | 15.00 | 0.00 | 4.90 | 0.30 | 9.183 | 4.00 | 0.00 | -0.092 | -0.472 | 0.009 |
| put | 17.50 | 0.00 | 4.90 | 1.65 | 7.970 | 1.00 | 0.00 | -0.114 | -0.480 | 0.011 |
| put | 20.00 | 0.00 | 4.90 | 0.00 | 6.888 | 0.00 | 0.00 | -0.139 | -0.475 | 0.013 |
| put | 22.50 | 0.00 | 4.90 | 0.05 | 5.965 | 7.00 | 0.00 | -0.165 | -0.463 | 0.014 |
| put | 25.00 | 0.00 | 4.90 | 0.10 | 5.154 | 315 | 0.00 | -0.195 | -0.444 | 0.016 |
| put | 30.00 | 0.10 | 5.00 | 1.60 | 1.258 | 644 | 0.00 | -0.128 | -0.084 | 0.012 |
| put | 35.00 | 0.10 | 4.90 | 8.50 | 2.228 | 3.00 | 0.00 | -0.377 | -0.229 | 0.022 |
| put | 40.00 | 3.20 | 4.10 | 13.70 | 0.884 | 21.00 | 0.00 | -0.563 | -0.228 | 0.023 |
| put | 45.00 | 6.60 | 10.00 | 0.00 | 1.910 | 0.00 | 0.00 | -0.628 | -0.302 | 0.022 |
| put | 50.00 | 11.30 | 15.00 | 21.88 | 2.375 | 0.00 | 0.00 | -0.666 | -0.348 | 0.021 |
| put | 55.00 | 16.30 | 20.00 | 0.00 | 2.761 | 0.00 | 0.00 | -0.718 | -0.339 | 0.019 |
| put | 60.00 | 21.70 | 25.00 | 0.00 | 3.095 | 0.00 | 0.00 | -0.902 | -0.114 | 0.010 |
| put | 65.00 | 26.60 | 30.00 | 0.00 | 3.389 | 0.00 | 0.00 | -0.909 | -0.120 | 0.009 |
| put | 70.00 | 31.20 | 35.00 | 46.00 | 3.650 | 0.00 | 0.00 | -0.915 | -0.124 | 0.009 |
| put | 75.00 | 36.60 | 40.00 | 0.00 | 3.888 | 0.00 | 0.00 | -0.920 | -0.128 | 0.009 |
Latest SEC filings
30| Filed | Form | Description | Period | Link |
|---|---|---|---|---|
| 2026-11-09 | 10-Q | Quarterly report pursuant to Section 13 or 15(d) | 2026-09-30 | SEC |
| 2026-11-09 | 8-K | Current report | 2026-11-09 | SEC |
| 2026-11-04 | 4 | Statement of changes in beneficial ownership of securities | 2026-11-02 | SEC |
| 2026-11-02 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-10-30 | 4 | Statement of changes in beneficial ownership of securities | 2026-10-29 | SEC |
| 2026-10-29 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-10-16 | 8-K | Current report | 2026-10-15 | SEC |
| 2026-10-02 | 4 | Statement of changes in beneficial ownership of securities | 2026-10-01 | SEC |
| 2026-10-02 | 4 | Statement of changes in beneficial ownership of securities | 2026-10-01 | SEC |
| 2026-10-01 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-29 | SEC |
| 2026-10-01 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-10-01 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-08 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-04 | SEC |
| 2026-09-04 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-02 | SEC |
| 2026-09-04 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-02 | SEC |
| 2026-09-04 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-04 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-02 | SEC |
| 2026-09-04 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-02 | SEC |
| 2026-09-03 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-01 | SEC |
| 2026-09-03 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-01 | SEC |
| 2026-09-03 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-01 | SEC |
| 2026-09-03 | 4 | Statement of changes in beneficial ownership of securities | 2026-09-01 | SEC |
| 2026-09-02 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-02 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-02 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-02 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-09-01 | 144 | Filing for proposed sale of securities under Rule 144. | SEC | |
| 2026-08-31 | 4 | Statement of changes in beneficial ownership of securities | 2026-08-28 | SEC |
| 2026-08-17 | 4 | Statement of changes in beneficial ownership of securities | 2026-08-13 | SEC |
| 2026-08-17 | 3 | Initial statement of beneficial ownership of securities | 2026-08-13 | SEC |
Insider activity by month
| Month | Bought | Buys | Sold | Sells |
|---|---|---|---|---|
| 2026-11 | 0 | 0 | 1.04M | 1 |
| 2026-10 | 0 | 0 | 1.61M | 3 |
| 2026-09 | 0 | 0 | 2.93M | 12 |
| 2026-08 | 0 | 0 | 1.57M | 3 |
| 2026-07 | 0 | 0 | 1.68M | 3 |
| 2026-06 | 0 | 0 | 1.49M | 5 |
| 2026-05 | 0 | 0 | 1.49M | 5 |
| 2026-04 | 0 | 0 | 705.81K | 3 |
| 2026-03 | 0 | 0 | 2.47M | 3 |
| 2026-02 | 0 | 0 | 920.55K | 2 |
| 2026-01 | 0 | 0 | 3.11M | 8 |
| 2025-12 | 0 | 0 | 5.37M | 5 |
| 2025-11 | 0 | 0 | 0 | 0 |
Institutional holders
| Manager | % owned |
|---|---|
| Frazier Life Sciences Management, L.P. | 9.09% |
| TRV GP IV, LLC | 8.08% |
| ARCH Venture Management, LLC | 7.44% |
| Deep Track Capital, LP | 6.74% |
| BlackRock, Inc. | 6.33% |
| Jupiter Topco LLC | 6.16% |
| T. Rowe Price Investment Management, Inc. | 4.70% |
| Logos Global Management LP | 3.50% |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.21% |
| a16z Capital Management, L.L.C. | 3.08% |
Funds
| Fund | % owned |
|---|---|
| VANGUARD TOTAL STOCK MARKET INDEX FUND | 2.55% |
| T. Rowe Price Capital Appreciation Fund | 1.77% |
| iShares Russell 2000 ETF | 1.66% |
| Select Biotechnology Portfolio | 1.42% |
| JPMorgan Small Cap Growth Fund | 0.76% |
| Fidelity Small Cap Index Fund | 0.70% |
| VANGUARD EXTENDED MARKET INDEX FUND | 0.59% |
| T. Rowe Price Small-Cap Stock Fund, Inc. | 0.53% |
| iShares Russell 2000 Growth ETF | 0.50% |
| T. Rowe Price Small-Cap Value Fund, Inc. | 0.50% |
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