OakChart

Ionis Pharmaceuticals Inc

IONSHealthcare·Biotechnology·USA·Mid·NASD·Nov 11 • 2:18 PM ET

28.63+0.44 (1.56%)
2026-11-11 20:19 CET
Market cap
4,684.73 USD m
Revenue, TTM
959.76 USD m
Net income, TTM
-546.14 USD m
Free cash flow, TTM
-616.26 USD m
EPS diluted, TTM
-3.33
P/E
-
Compare

Price

IONS against its 20, 50 and 200-day averages
2050200beat
40.0060.0080.0010.2M20.4MMay 26Jun 26Jul 26Aug 26Sep 26Oct 26Nov 26IONSclose 28.6320-day 40.8050-day 44.93200-day 65.0528.6352w high

67.0% under the 52-week high of 86.74 on 5 Feb 2026. 52-week low 27.75 on 9 Nov 2026. Last 15 sessions, 65.2% high to low

Profile

IONS
52-week range, 1% of the way up
27.7586.74

Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company was founded by Stanley T. Crooke, David J. Ecker, Christopher K. Mirabelli, and Brett P. Monia on January 10, 1989 and is headquartered in Carlsbad, CA.

IndexRUI
Employees1402
IPOMay 17, 1991
Beta0.46
ATR, 14d2.46
Rel volume0.89
Short float12.99%
Insider own1.97%
Inst own107.51%

Snapshot

6 groups

Valuation

IndexRUI
Market Cap4.77B
Enterprise Value5.06B
Income-546.14M
Sales959.76M
Book/sh2.37
Cash/sh11.31
Dividend Est.-
Dividend TTM-
Dividend Ex-Date-
Dividend Gr. 3/5Y- -
Payout-
Employees1402
IPOMay 17, 1991

Ratios

P/E-
Forward P/E-
PEG-
P/S4.97
P/B12.10
P/C2.53
P/FCF-
EV/EBITDA-
EV/Sales5.27
Quick Ratio5.36
Current Ratio5.43
Debt/Eq5.52
LT Debt/Eq5.17
Option/ShortYes / Yes

Earnings

EPS (ttm)-3.33
EPS next Y-2.84
EPS next Q-1.31
EPS this Y-46.42%
EPS next Y18.46%
EPS next 5Y39.36%
EPS past 3/5Y-7.82% 5.62%
Sales past 3/5Y17.12% 5.29%
EPS Y/Y TTM-106.48%
Sales Y/Y TTM-0.79%
EPS Q/Q17.80%
Sales Q/Q54.88%
EarningsNov 09 BMO
EPS/Sales Surpr.46.34% 36.39%

Ownership

Insider Own1.97%
Insider Trans-6.61%
Inst Own107.51%
Inst Trans3.49%
ROA-18.37%
ROE-107.98%
ROIC-22.49%
Gross Margin95.43%
Oper. Margin-58.91%
Profit Margin-56.90%
SMA20-29.83%
SMA50-36.28%
SMA200-55.98%
Trades-

Technical

Shs Outstand166.41M
Shs Float162.92M
Short Float12.99%
Short Ratio5.91
Short Interest21.17M
52W High86.74 -66.99%
52W Low27.75 3.17%
Volatility8.47% 4.83%
ATR (14)2.46
RSI (14)19.21
Beta0.46
Rel Volume0.89
Avg Volume3.58M
Volume2,389,413

Performance

Perf Week-28.69%
Perf Month-32.44%
Perf Quarter-48.76%
Perf Half Y-63.11%
Perf YTD-63.81%
Perf Year-60.48%
Perf 3Y-38.24%
Perf 5Y-14.69%
Perf 10Y-32.75%
Recom1.36
Target Price69.29
Prev Close28.19
Price28.63
Change %1.56%

Analyst ratings

latest 10 of 20
DateActionAnalystRating changeTargetImplied
Oct 22, 2026UpgradeBBMO Capital MarketsMarket Perform → Outperform$66+130.5%
Oct 15, 2026ResumedUUBSBuy$88+207.4%
Aug 19, 2026InitiatedBBMO Capital MarketsMarket Perform$60+109.6%
Jul 16, 2026DowngradeWWolfe ResearchOutperform → Peer Perform
May 19, 2026InitiatedCCitigroupBuy$115+301.7%
Apr 21, 2026InitiatedCCanaccord GenuityBuy$110+284.2%
Apr 10, 2026ResumedRRaymond JamesOutperform$104+263.3%
Jan 28, 2026ResumedBBarclaysOverweight$95+231.8%
Oct 08, 2025UpgradeJJP MorganNeutral → Overweight$80+179.4%
Sep 26, 2025UpgradeGGoldmanSell → Neutral$65+127.0%

Peers

Mkt cap
TickerCompanyMkt cap
ARWRArrowhead Pharmaceuticals Inc6.90B
ALNYAlnylam Pharmaceuticals Inc21.17B
BBIOBridgeBio Pharma Inc15.40B
WVEWave Life Sciences Inc672.19M
PHVSPharvaris NV2.40B
NTLAIntellia Therapeutics Inc1.61B
SLNSilence Therapeutics Plc ADR1.23B
BCRXBiocryst Pharmaceuticals Inc1.97B
BIIBBiogen Inc37.43B
AZNAstrazeneca plc286.64B

Insider trading

latest 14 of 100
InsiderRelationshipDateTransactionCostSharesValueTotal heldForm
Devers Shannon L.EVP, Chief Human Resources OfcOct 15 '26Option Exercise0.002,820019,168Oct 19 09:40 PM
Devers Shannon L.EVP, Chief Human Resources OfcOct 16 '26Sale43.541,35759,08217,811Oct 19 09:40 PM
Swayze EricEVP ResearchOct 15 '26Option Exercise0.001250443Oct 19 09:40 PM
Swayze EricEVP ResearchOct 16 '26Sale43.54532,308390Oct 19 09:40 PM
Devers Shannon L.OfficerOct 16 '26Proposed Sale44.001,35759,708Oct 16 05:16 PM
Hayden Michael RDirectorJul 30 '26Buy53.3815,000800,70019,000Jul 31 04:42 PM
Hayden Michael RDirectorJul 31 '26Buy51.605,000258,00024,000Jul 31 04:42 PM
HERMAN JOAN EDirectorJul 15 '26Option Exercise0.005,220051,306Jul 17 05:12 PM
BERTHELSEN SPENCER RDirectorJul 15 '26Option Exercise0.005,2200161,233Jul 17 05:12 PM
BENNETT C FRANKEVP, Chief Scientific OfficerJul 07 '26Sale85.4615,0001,281,9300Jul 09 07:26 PM
BENNETT C FRANKEVP, Chief Scientific OfficerJul 07 '26Sale83.585,536462,69375,018Jul 09 07:26 PM
Diaz Allene M.DirectorJul 07 '26Option Exercise47.1110,111476,32913,922Jul 09 06:07 PM
Diaz Allene M.DirectorJul 07 '26Sale85.4210,111863,6373,811Jul 09 06:07 PM
Kordasiewicz Holly B.EVP, Chief Development OfficerJul 07 '26Sale84.3036230,51722,096Jul 09 06:07 PM

Held by

AUM
TickerCompanyAUM
VTIVanguard Morningstar Total Stock Market ETFAUM: 687.42B
VBVanguard Morningstar Small-Cap ETFAUM: 79.59B
VBKVanguard Morningstar Small-Cap Growth ETFAUM: 22.34B
VXFVanguard Extended Market Index ETFAUM: 30.47B
XBIState Street SPDR S&P Biotech ETFAUM: 10.50B
CGGRCapital Group Growth ETFAUM: 25.66B
IBBiShares Biotechnology ETFAUM: 11.36B
ARKGARK Genomic Revolution ETFAUM: 1.97B
SCHASchwab U.S. Small-Cap ETFAUM: 22.25B
IWPiShares Russell Mid-Cap Growth ETFAUM: 18.09B

News

latest 14 of 200

Quarterly earnings

actual against estimate
PeriodReportedEPS actEPS estEPS repSales actSales estAnalysts
2026Q32026-11-09-0.660-1.230-0.660243178.1719
2026Q22026-07-29-0.690-1.089-0.693268189.118
2026Q12026-04-29-0.560-0.877-0.561246195.5617
2025Q42026-02-25-1.410-1.320-1.414203157.6815
2025Q32025-10-29-0.800-1.218-0.805157130.3319
2025Q22025-07-300.700-0.0910.678452298.319
2025Q12025-04-30-0.930-1.098-0.926132131.3917
2024Q42025-02-19-0.660-1.124-0.658227135.3318
2024Q32024-11-06-0.950-1.126-0.945134129.5720
2024Q22024-08-01-0.450-0.925-0.454225156.0918
2024Q12024-05-07-0.980-1.033-0.981119131.4218
2023Q42024-02-21-0.060-0.804-0.063325174.1219
2023Q32023-11-02-1.030-1.008-1.029144136.8620
2023Q22023-08-09-0.600-0.883-0.596188140.4417
2023Q12023-05-03-0.870-0.870-0.871131128.1516
2022Q42023-02-22-0.370-0.940-0.366152160.1317

Annual earnings

PeriodEPS actEPS estEPS repSales actSales est
2019FY2.0801.6782.0761,1231,029
2020FY-3.230-0.521-3.182729712.45
2021FY-0.200-1.448-0.203810650.76
2022FY-1.900-2.490-1.902587583.98
2023FY-2.560-3.282-2.558788637.1
2024FY-3.040-3.504-3.036705617.92
2025FY-2.380-2.281-2.380944900.07
2026FY--3.485--921.99
2027FY--2.842--1,171
2028FY--0.531--1,640
2029FY-1.569--2,098
2030FY-3.587--2,596

Estimate revisions

last 14 periods
PeriodTypeDateEstimatesUpDownMeanLowHigh
2026Q4S2026-11-0920217184.5124.96448
2026Q4S2026-11-061835234.89204.02448
2026Q4S2026-10-302135233.96204.02448
2026Q4S2026-10-282135233.96204448
2026Q4S2026-10-272136233.96204448
2026Q4S2026-10-232136233.96204448
2026Q4S2026-10-212136233.96204.02448
2026Q4S2026-10-202135234.08204.02448
2026Q4S2026-10-192125227.5489.34448
2026Q4S2026-10-162124228.4789.34448
2026Q4S2026-10-142124228.4789.34448
2026Q4S2026-10-132124228.4589.34448
2026Q4S2026-10-122024229.6189.34448
2026Q4S2026-10-0920315229.6189.34448

Estimate history

EPS, annual0.1492.0652.076-3.182-0.203-1.902-2.558-3.036-2.384-3.3295
Period201720182019202020212022202320242025TTM
EPS, quarterly-0.945-0.658-0.9260.678-0.805-1.414-0.561-0.693-0.662
PeriodQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26Q3 '26
Sales, annual514.179599.6741122.599729.264810.456587.367787.647705.138943.711959.76
Period201720182019202020212022202320242025TTM
Sales, quarterly133.814227131.612452.049156.719203246.091267.949242.721
PeriodQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26Q3 '26
Shares, annual124.976137.929140.34140.366141.21142.058144.341157.909163.305166.41
Period201720182019202020212022202320242025MRQ
Shares, quarterly157.813157.909159.041159.197161.138163.305165.902165.637166.41
PeriodQ3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26Q3 '26

Income statement, annual

Currency USD, millions
MetricTTM2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY
Total Revenue959.76943.71705.14787.65587.37810.46729.261,122.60599.67
Cost of Goods Sold Incl. D&A43.8828.3633.2031.6336.2230.4029.1120.3814.35
Gross Profit915.88915.36671.93756.02551.15780.05700.161,102.22585.33
Selling, General and Administrative Excl. Other1,481.301,297.041,147.011,109.75961.34810.24872.24736.34645.90
Research and Development921.09913.18901.53899.62833.15643.45535.08465.17413.37
Other Operating Expense0.000.000.000.000.000.000.000.000.00
Operating Income-565.42-381.68-475.08-353.73-410.19-30.19-172.08365.88-60.57
Interest Expense76.0790.5490.4581.468.129.359.5148.7744.79
Unusual Expense-22.71-10.222.89-11.497.33-1.48-16.5421.860.80
Net Income Before Taxes-543.80-379.60-460.07-333.96-257.99-29.15-134.55346.77-76.16
Income Taxes2.341.79-6.1732.3211.74-0.55345.1943.51-291.14
Consolidated Net Income-546.14-381.39-453.90-366.29-269.72-28.60-479.74305.68218.11
Net Income From Continuing Operations-546.14-381.39-453.90-366.29-269.72-28.60-444.26296.56276.87
Net Income-546.14-381.39-453.90-366.29-269.72-28.60-444.26296.56276.87
EPS (Recurring)-3.38-2.43-3.02-2.61-1.87-0.21-3.272.182.07
EPS (Basic, Before Extraordinaries)-3.33-2.38-3.04-2.56-1.90-0.20-3.182.122.09
EPS (Diluted)-3.33-2.38-3.04-2.56-1.90-0.20-3.182.082.07
EBITDA-535.13-358.99-453.09-331.23-388.09-10.63-154.92381.88-48.04
Non-Operating Income (Expense)74.9782.41108.3589.74167.668.9130.5051.5230.00
Other After Tax Adjustments0.000.000.000.000.000.000.002.423.13
Stock Option Compensation Expense138.13107.17103.4983.5979.2188.09167.99107.00103.74
Price To Earnings Ratio-------30.2729.25
Price To Sales Ratio7.7313.417.419.209.125.2910.827.6912.09
Gross Margin95.4397.0095.2995.9893.8396.2596.0198.1897.61
Operating Margin-58.91-40.45-67.37-44.91-69.84-3.72-23.6032.59-10.10
Net Margin-56.90-40.41-64.37-46.50-45.92-3.53-60.9226.4246.17
Shares Outstanding166.41163.30157.91144.34142.06141.21140.37140.34137.93
Market Capitalization4,684.734,684.735,520.087,258.255,365.234,297.027,905.598,497.457,437.14

Income statement, quarterly

Currency USD, millions
Metric2026Q32026Q22026Q12025Q42025Q32025Q22025Q12024Q4
Total Revenue242.72267.95246.09203.00156.72452.05131.61227.00
Cost of Goods Sold Incl. D&A11.1810.3810.4311.905.217.016.869.27
Gross Profit231.54257.57235.66191.10151.50445.03124.75217.73
Selling, General and Administrative Excl. Other362.24359.87353.08406.10311.69305.22271.61327.73
Research and Development215.14216.41210.17279.36217.13216.86200.76245.00
Other Operating Expense0.000.000.000.000.000.000.000.00
Operating Income-130.70-102.29-117.42-215.00-160.18139.82-146.86-110.00
Interest Expense8.7622.1222.5022.6922.1622.7622.9322.86
Unusual Expense-9.5310.18-22.58-0.79-29.9118.312.162.57
Net Income Before Taxes-110.11-113.38-92.31-228.00-128.39123.53-146.82-107.00
Income Taxes-0.141.260.221.000.21-0.020.12-3.00
Consolidated Net Income-109.97-114.65-92.53-229.00-128.61123.55-146.94-104.00
Net Income From Continuing Operations-109.97-114.65-92.53-229.00-128.61123.55-146.94-104.00
Net Income-109.97-114.65-92.53-229.00-128.61123.55-146.94-104.00
EPS (Recurring)-0.70-0.65-0.66-1.42-0.940.75-0.92-0.65
EPS (Basic, Before Extraordinaries)-0.66-0.69-0.56-1.41-0.810.78-0.93-0.66
EPS (Diluted)-0.66-0.69-0.56-1.41-0.810.68-0.93-0.66
EBITDA-122.84-94.66-109.98-207.66-155.68145.27-141.46-104.73
Non-Operating Income (Expense)19.8221.2225.038.9024.0524.7925.1328.43
Other After Tax Adjustments0.000.000.000.000.000.000.000.00
Stock Option Compensation Expense34.7336.0234.2033.1824.9523.4623.8728.44
Price To Sales Ratio7.7315.0111.7013.5910.807.636.677.83
Gross Margin95.3996.1395.7694.1496.6798.4594.7995.92
Operating Margin-53.85-38.18-47.72-105.91-102.2130.93-111.59-48.46
Net Margin-45.31-42.79-37.60-112.81-82.0627.33-111.64-45.81
Shares Outstanding166.41165.64165.90163.30161.14159.20159.04157.91
Market Capitalization4,684.7313,103.7012,404.2712,813.7610,427.366,288.374,795.975,520.08

Balance sheet, annual

Currency USD, millions
Metric2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY
Cash & Short Term Investments2,677.442,302.922,337.501,997.412,130.741,899.122,508.762,085.421,022.72
Short Term Receivables66.0692.1997.7825.5461.9076.2063.0312.7662.95
Inventories10.0512.5128.4322.0324.8121.9618.188.589.98
Other Current Assets237.09212.67178.15157.72127.60133.42130.62101.1273.08
Total Current Assets2,990.642,620.292,641.852,202.692,345.052,130.712,720.602,207.891,168.73
Net Property, Plant & Equipment361.60256.11242.94255.84196.07181.08166.25132.16121.91
Total Investments and Advances52.2141.0242.9940.3715.6215.0610.000.000.00
Intangible Assets----29.0027.9425.6724.0322.00
Deferred Tax Assets-----0.00305.56290.800.00
Other Assets119.3986.2562.2934.9725.9534.975.0312.9110.13
Total Assets3,523.843,003.682,990.072,533.882,611.692,389.763,233.112,667.781,322.77
Short Term Debt Incl. Current Port. of LT Debt453.159.2853.167.543.53316.112.0313.751.62
Accounts Payable28.0842.9626.0317.9211.9017.2016.0728.6624.89
Income Tax Payable2.710.032.156.250.041.3232.51--
Other Current Liabilities297.63257.04366.75279.86225.08264.26222.40237.88217.10
Total Current Liabilities781.57309.32448.09311.56240.55598.90273.00280.29243.61
Long Term Debt2,161.181,949.501,914.111,361.661,247.52623.53785.50632.97605.86
Provision for Risks Charges0.000.000.000.000.000.000.000.000.00
Other Liabilities92.00156.50241.18287.77351.88424.05490.06567.36108.03
Total Liabilities3,034.752,415.322,603.391,960.991,839.951,646.471,548.571,480.62957.49
Non-Equity Reserves0.000.000.000.000.000.000.000.000.00
Preferred Stock - Carrying Value0.000.000.000.000.000.000.000.000.00
Common Equity489.09588.35386.69572.89771.74743.281,471.091,048.08281.01
Total Shareholders Equity489.09588.35386.69572.89771.74743.281,471.091,048.08281.01
Accumulated Minority Interest0.000.000.000.000.000.00213.45139.0884.27
Total Equity489.09588.35386.69572.89771.74743.281,684.551,187.16365.28
Total Liabilities & Stockholders Equity3,523.843,003.682,990.072,533.882,611.692,389.763,233.112,667.781,322.77
Book Value Per Share2.993.732.684.035.475.3010.487.602.25
Tangible Book Value Per Share2.993.732.684.035.265.1010.307.422.07
Full-Time Employees1,4021,069927796660757817737547
Price to Book Ratio11.928.3323.009.025.579.415.767.1120.35
Return on Assets-11.69-15.15-13.26-10.48-1.14-15.8010.0513.881.68
Return on Equity-70.80-93.10-76.34-40.12-3.54-40.1323.5440.169.88
Return on Invested Capital-14.39-17.89-15.92-13.94-1.42-32.5013.1416.472.12
Quick Ratio3.818.435.837.009.653.529.907.854.76
Current Ratio3.838.475.907.079.753.569.977.884.80

Cash flow, annual

Currency USD, millions
MetricTTM2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY
Net Income-546.54-381.39-453.90-366.29-269.72-28.60-479.74303.26214.99
Depreciation30.2822.6921.9922.5022.1119.5617.1615.9912.53
Other Funds (Non Cash)168.04141.32140.35113.53-34.32153.65230.30202.27166.48
Funds from Operations-348.22-217.37-291.56-230.25-281.94144.62109.45514.43103.48
Extraordinary Item0.000.000.000.000.000.000.000.000.00
Changes in Working Capital-196.20-51.22-209.39-77.267.57-113.82-73.56-168.71499.41
Income Taxes Payable0.012.68-2.12-4.106.21-1.29-31.1931.66-0.71
Cash from Operating Activities-544.41-268.58-500.95-307.51-274.3730.8035.89345.72602.89
Capital Expenditures-78.35-57.08-50.34-28.01-20.10-17.90-41.05-36.28-17.65
Net Assets From Acquisitions0.000.000.000.000.000.000.000.00-
Sale of Fixed Assets and Businesses0.000.000.000.02254.080.000.000.00-
Purchase or Sale of Investments319.04-220.69-83.69-186.14-496.62212.81315.52-4.99-911.91
Purchase of Investments-1,498.24-1,918.56-1,852.86-1,770.81-1,485.77-1,131.38-1,570.41-1,956.73-1,794.73
Sale Or Maturity of Investments1,817.291,697.871,769.171,584.68989.151,344.181,885.931,951.73882.82
Other Uses0.000.000.000.000.000.000.000.000.00
Other Sources0.000.000.000.000.000.000.000.000.00
Cash from Investing Activities240.69-277.78-134.03-214.13-262.64194.91274.48-41.27-929.56
Cash Dividends Paid0.000.000.000.000.000.000.000.000.00
Change in Capital Stock211.21192.60522.7349.446.3785.71-38.51141.38475.87
Repurchase of Common Pref Stock0.000.000.000.000.000.00-90.55-34.390.00
Sale of Common Pref Stock211.21192.60522.7349.446.3785.7152.04175.77475.87
Proceedsfrom Stock Options18.610.000.000.000.00-15.610.000.00447.96
Issuance or Reduction of Debt, Net50.72483.24-44.67562.29-50.69313.570.00-22.110.00
Change in Long Term Debt50.72483.24-44.67562.29-50.69313.570.00-22.110.00
Issuance of Long Term Debt770.00770.000.001,075.000.00632.500.00109.500.00
Reduction of Long Term Debt-719.28-286.76-44.67-512.71-50.69-318.930.00-131.610.00
Net Financing Active Other Cash Flow0.000.000.0032.35-10.98-153.34-558.10-19.240.00
Other Financing Activities Uses0.000.000.000.00-10.98-153.34-558.10-19.240.00
Cash from Financing Activities261.93675.84478.06644.08-55.30245.93-596.61100.02475.87
Exchange Rate Effect-0.240.70-0.270.35-0.42-0.110.62--
Net Change in Cash-42.04130.18-157.19122.79-592.72471.53-285.62404.47149.19
Free Cash Flow-616.26-320.03-546.23-331.32-290.0918.840.77314.81585.24
Preferred Dividends (Cash Flow)-0.000.000.000.000.000.000.000.00
Price to Free Cash Flow-----227.7310,224.9527.4212.38
Deferred Taxes & Investment Tax Credit-0.000.000.000.000.00341.73-7.10-290.52

Balance sheet, quarterly

Currency USD, millions
Metric2026Q32026Q22026Q12025Q42025Q32025Q2
Cash & Short Term Investments1,883.912,054.591,977.062,677.442,243.432,292.97
Short Term Receivables88.3458.8473.6866.0624.6152.58
Inventories28.5850.835.5610.0510.478.48
Other Current Assets360.68327.01880.64237.09240.49223.12
Total Current Assets2,361.502,491.272,936.952,990.642,518.992,577.15
Net Property, Plant & Equipment390.09386.69377.46361.60348.11275.88
Total Investments and Advances19.8219.8219.8252.2152.2122.82
Other Assets141.1896.72115.74119.39113.78109.28
Total Assets2,912.592,994.503,449.973,523.843,033.092,985.13
Short Term Debt Incl. Current Port. of LT Debt138.1912.92443.43453.15644.88643.70
Accounts Payable27.1147.7026.0328.0814.3322.80
Income Tax Payable0.112.882.872.710.100.08
Other Current Liabilities269.88252.13244.26297.63244.14230.65
Total Current Liabilities435.29315.64716.59781.57903.46897.24
Long Term Debt2,034.902,176.102,166.222,161.181,403.761,331.08
Provision for Risks Charges0.000.000.000.000.000.00
Other Liabilities48.7663.0375.7592.00107.91125.09
Total Liabilities2,518.952,554.762,958.553,034.752,415.122,353.41
Non-Equity Reserves0.000.000.000.000.000.00
Preferred Stock - Carrying Value0.000.000.000.000.000.00
Common Equity393.64439.74491.41489.09617.97631.72
Total Shareholders Equity393.64439.74491.41489.09617.97631.72
Accumulated Minority Interest0.000.000.000.000.000.00
Total Equity393.64439.74491.41489.09617.97631.72
Total Liabilities & Stockholders Equity2,912.592,994.503,449.973,523.843,033.092,985.13
Book Value Per Share2.372.652.962.993.843.97
Tangible Book Value Per Share2.372.652.962.993.843.97
Full-Time Employees---1,402--
Price to Book Ratio11.9226.7725.0720.6316.4913.21
Return on Assets-18.37-18.89-10.43-11.67-8.37-9.44
Return on Equity-107.98-105.42-67.54-70.72-39.99-59.83
Return on Invested Capital-4.53-4.38-3.48-8.64-6.366.29
Quick Ratio5.367.734.093.812.782.86
Current Ratio5.437.894.103.832.792.87

Cash flow, quarterly

Currency USD, millions
Metric2026Q32026Q22026Q12025Q42025Q32025Q2
Net Income-109.97-114.65-92.53-229.39-128.61123.55
Depreciation7.867.647.457.344.505.45
Other Funds (Non Cash)23.8361.3322.3960.49-1.9250.82
Funds from Operations-78.28-45.68-62.70-161.56-126.02179.82
Extraordinary Item0.000.000.000.000.000.00
Changes in Working Capital-101.14611.21-730.1223.86-5.41-28.48
Income Taxes Payable-2.770.000.162.610.0226.02
Cash from Operating Activities-179.42565.53-792.82-137.71-131.44151.34
Capital Expenditures-14.21-18.23-23.25-22.66-6.93-14.27
Net Assets From Acquisitions0.000.000.000.000.000.00
Sale of Fixed Assets and Businesses0.000.000.000.000.000.00
Purchase or Sale of Investments114.0941.73560.07-396.8598.27-105.80
Purchase of Investments-193.27-320.25-192.75-791.97-323.94-491.59
Sale Or Maturity of Investments307.36361.98752.82395.12422.21385.79
Other Uses0.000.000.000.000.000.00
Other Sources0.000.000.000.000.000.00
Cash from Investing Activities99.8823.50536.82-419.5091.34-120.07
Cash Dividends Paid0.000.000.000.000.000.00
Preferred Dividends (Cash Flow)0.000.000.000.000.000.00
Change in Capital Stock25.8320.2657.30107.8281.261.29
Repurchase of Common Pref Stock0.000.000.000.000.000.00
Sale of Common Pref Stock25.8320.2657.30107.8281.261.29
Proceedsfrom Stock Options25.8320.2657.30-84.7981.261.29
Issuance or Reduction of Debt, Net-0.04-432.55-0.04483.36-0.04-0.04
Change in Long Term Debt-0.04-432.55-0.04483.36-0.04-0.04
Issuance of Long Term Debt0.000.000.00770.000.000.00
Reduction of Long Term Debt-0.04-432.55-0.04-286.64-0.04-0.04
Net Financing Active Other Cash Flow0.000.000.000.000.000.00
Other Financing Activities Uses0.000.000.000.000.000.00
Cash from Financing Activities25.79-412.2957.26591.1881.221.25
Exchange Rate Effect-0.01-0.05-0.14-0.04-0.080.59
Net Change in Cash-53.76176.68-198.8833.9241.0433.11
Free Cash Flow-192.13549.45-814.58-159.00-136.71139.03

Revenue breakdown

Collaborative Agreement2024: 332.65M 2025: 465.79M
Other Commercial2024: 35.77M 2025: 35.00M
Product2025: 115.32M
Royalty2024: 257.31M 2025: 285.53M
Wainua Joint Development2024: 79.42M 2025: 42.08M
United States2024: 705.14M 2025: 943.71M

Short interest

shares short against float, oldest to newest
SettlementOf floatShares shortFloatAvg volume
2026-10-3012.99%21.2M162.9M3.14M
2026-10-1512.68%20.7M162.9M3.30M
2026-09-3013.82%22.5M162.9M3.75M
2026-09-1512.82%20.9M162.9M3.32M
2026-08-3112.84%20.9M162.9M2.92M
2026-08-1412.83%20.9M162.9M2.84M
2026-07-3113.18%21.5M162.9M2.75M
2026-07-1512.37%20.0M162.0M2.49M
2026-06-3010.75%17.4M162.0M1.83M
2026-06-1510.96%17.8M162.0M1.85M
2026-05-2910.48%17.0M162.1M1.98M
2026-05-159.93%16.1M162.1M2.08M
2026-04-3010.05%16.3M162.0M2.13M
2026-04-158.50%13.8M162.0M2.24M
2026-03-318.86%14.3M161.8M2.35M
2026-03-138.62%13.9M161.8M2.18M
2026-02-279.47%15.3M161.8M2.09M
2026-02-139.76%15.5M158.6M2.16M
2026-01-309.80%15.5M158.6M2.46M
2026-01-158.65%13.7M158.7M2.32M

Option chain

expiry 2026-11-20
TypeStrikeBidAskLastIVOpen intVolumeDeltaThetaVega
call15.0012.3016.000.005.4070.000.000.937-0.1040.006
call17.509.8013.500.004.7050.000.000.921-0.0980.007
call20.007.3011.000.003.8470.000.000.900-0.0920.008
call22.504.808.600.003.1480.000.000.870-0.0840.009
call25.002.405.600.002.0992.000.000.819-0.0710.012
call27.501.702.102.150.83711858.000.661-0.0680.016
call30.000.600.750.700.72323852.000.365-0.0710.017
call32.500.100.250.190.7451064540.152-0.0440.011
call35.000.050.100.100.89531.002.000.086-0.0360.007
call37.500.000.550.151.1171.000.000.072-0.0390.006
call40.000.000.100.051.2023,0440.000.048-0.0300.004
call42.500.002.150.091.3411880.000.043-0.0310.004
call45.000.000.050.051.5162,7220.000.039-0.0320.004
call47.500.000.050.051.4612650.000.022-0.0190.002
call50.000.000.400.351.5801,4870.000.020-0.0200.002
call52.500.000.250.201.7101400.000.019-0.0190.002
call55.000.000.100.051.8641,6110.000.018-0.0210.002
call57.500.002.150.251.9693.000.000.017-0.0210.002
call60.000.001.200.302.06753.000.000.017-0.0220.002
call62.500.002.155.002.1611.000.000.016-0.0220.002
call65.000.000.050.022.1813670.000.016-0.0200.002
call67.500.000.950.152.30010.000.000.015-0.0220.002
call70.000.002.150.102.38137.000.000.015-0.0230.002
call75.000.002.150.102.5692.000.000.014-0.0230.002
call80.000.002.150.462.6806.000.000.013-0.0230.002
call85.000.001.150.002.7890.000.000.013-0.0240.002
call90.000.000.950.002.9110.000.000.012-0.0240.001
put15.000.002.150.003.3110.000.00-0.061-0.1020.006
put17.500.001.750.002.6660.000.00-0.076-0.0970.007
put20.000.001.750.002.1150.000.00-0.095-0.0910.008
put22.500.001.200.001.6080.000.00-0.123-0.0830.009
put25.000.000.500.001.1221.000.00-0.169-0.0710.011
put27.500.150.700.450.67735783.00-0.339-0.0650.016
put30.001.502.201.800.7773872.00-0.635-0.0670.017
put32.503.105.003.721.3884.000.00-0.848-0.0410.011
put35.004.607.807.102.0641030.00-0.878-0.0470.009
put37.508.208.808.601.4091,6616.00-0.928-0.0350.006
put40.009.6012.2011.242.0643653.00-0.952-0.0260.004
put42.5012.1015.2014.002.7823580.00-0.957-0.0270.004
put45.0014.6017.7016.282.9113232.00-0.977-0.0140.002
put47.5017.2020.2017.343.1132120.00-0.978-0.0140.002
put50.0020.0022.7019.253.29346.000.00-0.980-0.0150.002
put52.5021.5025.2023.753.4721.000.00-0.981-0.0150.002
put55.0024.0027.7011.703.63412.000.00-0.982-0.0150.002
put57.5026.5030.206.103.78637.000.00-0.983-0.0150.002
put60.0029.0032.7014.883.9298.000.00-0.983-0.0150.002
put62.5031.5035.2017.764.06417.000.00-0.984-0.0150.002
put65.0034.0037.700.004.1920.000.00-0.984-0.0150.002
put67.5036.5040.200.004.3140.000.00-0.985-0.0150.002
put70.0039.0042.700.004.4300.000.00-0.985-0.0150.002
put75.0044.0047.700.004.6470.000.00-0.986-0.0150.002
put80.0049.0052.700.004.8460.000.00-0.987-0.0150.002
put85.0054.0057.700.005.0300.000.00-0.987-0.0140.001
put90.0059.0062.700.005.2010.000.00-0.988-0.0140.001

Latest SEC filings

30
FiledFormDescriptionPeriodLink
2026-11-098-KCurrent report2026-11-09SEC
2026-11-0910-QQuarterly report pursuant to Section 13 or 15(d)2026-09-30SEC
2026-10-238-KCurrent report2026-10-23SEC
2026-10-218-KCurrent report2026-10-20SEC
2026-10-194Statement of changes in beneficial ownership of securities2026-10-15SEC
2026-10-194Statement of changes in beneficial ownership of securities2026-10-15SEC
2026-10-16144Filing for proposed sale of securities under Rule 144.SEC
2026-09-238-KCurrent report2026-09-23SEC
2026-09-048-KCurrent report2026-09-04SEC
2026-09-048-KCurrent report2026-09-03SEC
2026-09-024Statement of changes in beneficial ownership of securities2026-08-31SEC
2026-09-024Statement of changes in beneficial ownership of securities2026-08-31SEC
2026-09-024Statement of changes in beneficial ownership of securities2026-08-31SEC
2026-09-024Statement of changes in beneficial ownership of securities2026-08-31SEC
2026-07-31S-8Initial registration statement for securities to be offered to employees pursuant to employee benefit plansSEC
2026-07-314Statement of changes in beneficial ownership of securities2026-07-30SEC
2026-07-298-KCurrent report2026-07-29SEC
2026-07-2910-QQuarterly report pursuant to Section 13 or 15(d)2026-06-30SEC
2026-07-174Statement of changes in beneficial ownership of securities2026-07-15SEC
2026-07-174Statement of changes in beneficial ownership of securities2026-07-15SEC
2026-07-174Statement of changes in beneficial ownership of securities2026-07-15SEC
2026-07-174Statement of changes in beneficial ownership of securities2026-07-15SEC
2026-07-108-KCurrent report2026-07-09SEC
2026-07-098-KCurrent report2026-07-09SEC
2026-07-094Statement of changes in beneficial ownership of securities2026-07-07SEC
2026-07-094Statement of changes in beneficial ownership of securities2026-07-07SEC
2026-07-094Statement of changes in beneficial ownership of securities2026-07-07SEC
2026-07-07144Filing for proposed sale of securities under Rule 144.SEC
2026-07-07144Filing for proposed sale of securities under Rule 144.SEC
2026-07-064Statement of changes in beneficial ownership of securities2026-07-01SEC

Insider activity by month

MonthBoughtBuysSoldSells
2026-110000
2026-100061.39K2
2026-090000
2026-080000
2026-071.06M23.55M5
2026-060016.13M10
2026-05006.54M2
2026-04003.50M7
2026-030047.43M16
2026-020011.27M4
2026-010024.14M24
2025-12002.26M1
2025-11008.85M7

Institutional holders

Manager% owned
FMR LLC14.89%
Capital World Investors13.11%
BlackRock, Inc.6.48%
VANGUARD PORTFOLIO MANAGEMENT LLC4.76%
WELLINGTON MANAGEMENT GROUP LLP4.63%
VANGUARD CAPITAL MANAGEMENT LLC4.36%
TWO SIGMA INVESTMENTS, LP3.78%
ROYAL BANK OF CANADA3.74%
Focus Partners Wealth3.22%
PICTON MAHONEY ASSET MANAGEMENT3.03%

Funds

Fund% owned
NYLIM MacKay Convertible Fund10.69%
NYLIM VP MacKay Convertible Portfolio7.48%
Virtus Income & Growth Fund6.12%
Fidelity Growth Company Fund5.12%
Growth Fund of America4.61%
Invesco Convertible Securities Fund3.75%
VANGUARD HEALTH CARE FUND3.74%
SMALLCAP World Fund Inc3.18%
Virtus Convertible Fund3.03%
VANGUARD TOTAL STOCK MARKET INDEX FUND3.02%

OakChart. IONS. Cached 15 minutes.