Unprecedented demand for LLY and NVO

In a time of economic uncertainty, one industry has remarkably stood strong: the pharmaceutical sector, specifically in the burgeoning market for weight-loss drugs. Leading the charge are Novo Nordisk and Eli Lilly, both facing skyrocketing demand for their innovative treatments.

Eli Lilly, headquartered in Indianapolis and ranked 142nd on the Fortune 500, has recently gained significant momentum with its Type 2 diabetes medication, Mounjaro, and its newly approved obesity drug, Zepbound. These drugs have propelled the company’s growth, as evidenced by their Q1 revenue increase of 26%. CFO Anat Ashkenazi highlighted on a recent earnings call that Mounjaro achieved global sales of $1.8 billion, with $1.5 billion from the U.S. alone. This growth has prompted Eli Lilly to raise its revenue projections to as much as $43.6 billion for the year.

However, with success comes challenges. “Unprecedented demand” has resulted in backorders for both Mounjaro and Zepbound, creating frustration for patients experiencing prescription delays. Ashkenazi assured stakeholders that the company is rapidly increasing production capacity to meet this demand. Expansion plans include seven manufacturing sites globally, some of which are currently ramping up or under construction.

Novo Nordisk, based in Denmark and ranked 151st on the Fortune 500 Europe, also faces surging demand for its popular drugs Ozempic and Wegovy. In its Q1 report, Novo Nordisk revealed a 24% increase in net sales, primarily driven by its diabetes and obesity care products, which grew by 25%. However, even with the company commanding around 56% of the GLP-1 diabetes drug market, periodic supply constraints were reported due to the overwhelming demand.

To address these supply issues, Novo Nordisk is expanding its manufacturing capacity. It plans to acquire Catalent, a major drug manufacturing contractor, for $16.5 billion and to purchase three of its manufacturing sites for $11 billion. These strategic moves aim to bolster production capabilities and meet the growing global demand for their products.

Both companies are making significant strides in the weight-loss drug market, which is expected to grow exponentially. Mark Purcell, a European Biopharmaceuticals analyst at Morgan Stanley, projects that the global market for obesity drugs could reach $77 billion by 2030. While supply shortages may hinder immediate growth, Purcell emphasizes that the industry’s expanding pipeline promises new and innovative treatment options.

As Novo Nordisk and Eli Lilly continue to innovate and scale up production, their efforts are set to shape the future of weight-loss treatments, marking this sector as one to watch closely in the coming years.